Session 13

Date: Tues. 5/12/09

Topics and Speakers:

Ophthalmologic Complications, Steve Sanislo, MD (Ophthalmology)

Cardiovascular Complications, Michael McConnell, MD

Topic 1: Ophthalmologic Complications

The lecture slides can be found here.

Topic 2: Cardiovascular Complications

Learning Objectives: After attending this session, the learner should be able to:

identify the major components of the cardiovascular system
describe the basic anatomy and function of the cardiovascular system
identify major disorders of the cardiovascular system
appreciate different ways in which diabetes affects large and small blood vessels
describe how diabetes causes or exacerbates cardiovascular disease, including diseases of other organs such as the eye (diabetic retinopathy)

Key words: arterial tree, arteries, arterioles, capillaries, venules, veins; endothelium; oxidation/oxidative stress; atherosclerosis, plaque

Assignment: Work through the cardiovascular physiology module of the SUMMIT physiology package (available without password from the Stanford network)

Supplementary Resources

FOR THE CLASSIC STUDY DEMONSTRATING THE RELATIONSHIP BETWEEN BLOOD GLUCOSE CONTROL AND COMPLICATIONS SEE:

The Diabetes Control and Complications Trial Research Group. 1993. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329:977-986. On-line at http://content.nejm.org/cgi/content/full/329/14/977
Lasker RD. 1993. The Diabetes Control and Complications Trial --Implications for Policy and Practice. N. Engl J. Med. 329:1035-1036.On-line at http://content.nejm.org/cgi/content/full/329/14/1035